Hapgen ® Spray

Generic Name：recombinant human interferon α1b spray

Proprietary Name：Hapgen

【Indications】for the local treatment of initial or recurrent facial herpes simplex caused by the virus

【Specification】5ml each, containing recombinant human interferon 1b 0.25 mU (25 g)

【Usage and dosage】external skin use, spraying in the affected area, 1-2 spray per time(80-120 l per spray), so that the drug can cover the entire skin damage area, 4-6 times a day, until the skin damage is healed

【Product features】

1. Exclusive interferon α1b spray product

2. With concentrated local drug use effect, small drug dosage and good safety

3. Early application promotes scab, shorten the course of disease and reduce recurrence

【Storage】storage and transport at 2~8℃

【Packaging】consists of polyethylene bottles and medicinal aerosol pumps. 1 bottle/box, 200 bottles/piece

【Validity period】24 months

【Approval Document No.】National Medicine Permit No. S20110016

* This part is for professional reference only

Hapgen ® eye drops

Generic Name：human interferon α1b eye drops

Proprietary Name：Hapgen

【Indications】for the treatment of herpes simplex virus keratitis (epithelial type)

【Specification】2ml per bottle, containing recombinant human interferon α1b 200,000 IU (20 micrograms)

【Usage and dosage】4-6 times a day, 1-2 drops each time, the dosage can be reduced or stopped as appropriate with the improvement of the condition

【Product features】

1. Different antiviral mechanism from nucleoside drugs, no drug resistance; still effective for nucleoside drug resistance users

2. Combined with nucleoside drugs to produce a synergistic effect, improve the cure rate, and control the recurrence

3. The concentrated effect of local drug use, smaller drug dosage and better safety

【Storage】2~8℃ for light avoidance storage and transportation

【Packaging】low-density polyethylene eye drop bottle, 1 bottle/box, 200 bottles/piece

【Validity period】24 months

【Approval Document No.】National Medicine Permit No. S20130003

* This part is for professional reference only

Hapgen ® powder injection

Generic Name：injected human interferon α1b

Proprietary Name：Hapgen

【Indications】chronic hepatitis B, chronic hepatitis C, hair cell leukemia, condyloma acuminatum, chronic cervicitis, herpetic keratitis, herpes zoster, epidemic hemorrhagic fever, pediatric respiratory syncytial viral pneumonia, chronic myelogenous leukemia, mela

【Specification】10 g/bottle、30 g/bottle、50 g/bottle

【Usage and dosage】dissolved with 1ml of sterilized water, injected intramuscularly or subcutaneously, once a day or every other day

【Product features】

1. better safety——the gene comes from the white blood cells of healthy Chinese people, which is in line with the natural state of Chinese people, with mild adverse reactions and less neutralizing antibody production

2. Stronger antiviral effect——cell signaling molecule STAT1 is higher than that with other interferon subtypes

3 Stronger immunity——increases mononuclear MHC expression and has stronger immunophagocytosis

【Storage】Storage and transport at 2~8℃

【Validity period】30 months

* This part is for professional reference only

Hapgen® injection

Generic Name：Human interferon α1b injection

Proprietary Name：Hapgen

【Indications】chronic hepatitis B, chronic hepatitis C, hair cell leukemia, condyloma acuminatum, chronic cervicitis, herpetic keratitis, herpes zoster, epidemic hemorrhagic fever, pediatric respiratory syncytial viral pneumonia, chronic myelogenous leukemia, mela

【Specification】6-50μg: 0.5-1ml/ bottle

【Usage and dosage】Intramuscular, subcutaneous and focal injections, once a day or every other day

【Product features】

1. Good safety —— gene comes from white blood cells of healthy Chinese people, conform to the natural state of Chinese people, with light adverse reactions and less neutralizing antibodies; the only domestic interferon product approved by NMPA for pediatric clinical trials, clinical approval No.: 2005L3205

2. Stronger antiviral effect——cell signaling molecule STAT1 is higher than that with other interferon subtypes

3 Stronger immunity——increases mononuclear MHC expression and has stronger immunophagocytosis

【Storage】Storage and transport at 2~8℃

【Validity period】24 months

* This part is for professional reference only